Plasmidic qnr Genes Confer Clinical Resistance to Ciprofloxacin under Urinary Tract Physiological Conditions

Escherichia coli variants expressing plasmid-mediated qnr genes are usually susceptible to fluoroquinolones by standard susceptibility testing. Here we show that, under specific urinary tract physiological conditions, susceptible laboratory and clinical strains harboring qnr determinants become full...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Martín-Gutiérrez, Guillermo, Rodríguez-Martínez, José Manuel, Pascual, Álvaro, Rodríguez-Beltrán, Jerónimo, Blázquez, Jesús
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365700/
https://ncbi.nlm.nih.gov/pubmed/28096153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02615-16
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