Nanoliposomal Buparvaquone Immunomodulates Leishmania infantum-Infected Macrophages and Is Highly Effective in a Murine Model

Visceral leishmaniasis is a fatal parasitic neglected disease affecting 1.5 million people worldwide. Based on a drug repositioning approach, the aim of this work was to investigate the in vitro immunomodulatory potential of buparvaquone (BPQ) and to establish a safe regimen to evaluate the in vivo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: da Costa-Silva, Thais Alves, Galisteo, Andrés Jimenez, Lindoso, José Angelo Lauletta, Barbosa, Leandro R. S., Tempone, Andre Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365673/
https://ncbi.nlm.nih.gov/pubmed/28167544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02297-16
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