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Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages

BACKGROUND: The dominant, cell surface lipophosphoglycan (LPG) of Leishmania is a multifunctional molecule involved in the interaction with vertebrate and invertebrate hosts. Although the role of LPG on infection has been extensively studied, it is not known if LPG interspecies variations contribute...

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Bibliografske podrobnosti
Main Authors: Ibraim, Izabela Coimbra, de Assis, Rafael Ramiro, Pessoa, Natália Lima, Campos, Marco Antônio, Melo, Maria Norma, Turco, Salvatore Joseph, Soares, Rodrigo Pedro
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606350/
https://ncbi.nlm.nih.gov/pubmed/23497381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-6-54
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