Two biochemically distinct lipophosphoglycans from Leishmania braziliensis and Leishmania infantum trigger different innate immune responses in murine macrophages

BACKGROUND: The dominant, cell surface lipophosphoglycan (LPG) of Leishmania is a multifunctional molecule involved in the interaction with vertebrate and invertebrate hosts. Although the role of LPG on infection has been extensively studied, it is not known if LPG interspecies variations contribute...

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Main Authors: Ibraim, Izabela Coimbra, de Assis, Rafael Ramiro, Pessoa, Natália Lima, Campos, Marco Antônio, Melo, Maria Norma, Turco, Salvatore Joseph, Soares, Rodrigo Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606350/
https://ncbi.nlm.nih.gov/pubmed/23497381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-6-54
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