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Pharmacokinetics of Benznidazole in Healthy Volunteers and Implications in Future Clinical Trials

Despite its toxicity and low efficacy in the chronic phase, benznidazole is the drug of choice in Chagas disease. Scarce information about pharmacokinetics and pharmacodynamics of benznidazole has been published. We performed a phase I, open-label, nonrandomized pharmacokinetic study of benznidazole...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Molina, I., Salvador, F., Sánchez-Montalvá, A., Artaza, M. A., Moreno, R., Perin, L., Esquisabel, A., Pinto, L., Pedraz, J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365666/
https://ncbi.nlm.nih.gov/pubmed/28167552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01912-16
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