A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading

Synthetic peptides derived from the heptad repeat (HR) of fusion (F) proteins can be used as dominant negative inhibitors to inhibit the fusion mechanism of class I viral F proteins. Here, we have performed a stapled-peptide scan across the HR2 domain of the respiratory syncytial virus (RSV) F prote...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gaillard, Vanessa, Galloux, Marie, Garcin, Dominique, Eléouët, Jean-François, Le Goffic, Ronan, Larcher, Thibaut, Rameix-Welti, Marie-Anne, Boukadiri, Abdelhak, Héritier, Julien, Segura, Jean-Manuel, Baechler, Elodie, Arrell, Miriam, Mottet-Osman, Geneviève, Nyanguile, Origène
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365662/
https://ncbi.nlm.nih.gov/pubmed/28137809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02241-16
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