A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading

Synthetic peptides derived from the heptad repeat (HR) of fusion (F) proteins can be used as dominant negative inhibitors to inhibit the fusion mechanism of class I viral F proteins. Here, we have performed a stapled-peptide scan across the HR2 domain of the respiratory syncytial virus (RSV) F prote...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Gaillard, Vanessa, Galloux, Marie, Garcin, Dominique, Eléouët, Jean-François, Le Goffic, Ronan, Larcher, Thibaut, Rameix-Welti, Marie-Anne, Boukadiri, Abdelhak, Héritier, Julien, Segura, Jean-Manuel, Baechler, Elodie, Arrell, Miriam, Mottet-Osman, Geneviève, Nyanguile, Origène
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2017
Onderwerpen:
Antiviral Agents
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365662/
https://ncbi.nlm.nih.gov/pubmed/28137809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02241-16
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