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Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes

Pregestational diabetes is highly associated with an increased risk of birth defects. However, factors that can increase or reduce the expressivity and penetrance of malformations in pregnancies in women with diabetes remain poorly identified. All-trans retinoic acid (RA) plays crucial roles in embr...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Lee, Leo M.Y., Leung, Maran B.W., Kwok, Rachel C.Y., Leung, Yun Chung, Wang, Chi Chiu, McCaffery, Peter J., Copp, Andrew J., Shum, Alisa S.W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365142/
https://ncbi.nlm.nih.gov/pubmed/28087565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1570
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