Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes

Pregestational diabetes is highly associated with an increased risk of birth defects. However, factors that can increase or reduce the expressivity and penetrance of malformations in pregnancies in women with diabetes remain poorly identified. All-trans retinoic acid (RA) plays crucial roles in embr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes
Prif Awduron: Lee, Leo M.Y., Leung, Maran B.W., Kwok, Rachel C.Y., Leung, Yun Chung, Wang, Chi Chiu, McCaffery, Peter J., Copp, Andrew J., Shum, Alisa S.W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5365142/
https://ncbi.nlm.nih.gov/pubmed/28087565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1570
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