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A paradoxical teratogenic mechanism for retinoic acid
Retinoic acid, an active metabolite of vitamin A, plays essential signaling roles in mammalian embryogenesis. Nevertheless, it has long been recognized that overexposure to vitamin A or retinoic acid causes widespread teratogenesis in rodents as well as humans. Although it has a short half-life, exp...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427051/ https://ncbi.nlm.nih.gov/pubmed/22869719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200872109 |
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