A paradoxical teratogenic mechanism for retinoic acid

Retinoic acid, an active metabolite of vitamin A, plays essential signaling roles in mammalian embryogenesis. Nevertheless, it has long been recognized that overexposure to vitamin A or retinoic acid causes widespread teratogenesis in rodents as well as humans. Although it has a short half-life, exp...

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Bibliografische gegevens
Hoofdauteurs: Lee, Leo M. Y., Leung, Chun-Yin, Tang, Walfred W. C., Choi, Heung-Ling, Leung, Yun-Chung, McCaffery, Peter J., Wang, Chi-Chiu, Woolf, Adrian S., Shum, Alisa S. W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427051/
https://ncbi.nlm.nih.gov/pubmed/22869719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200872109
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