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Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis.

Serotonin (5-HT) stimulated the release of arachidonic acid in hippocampal neurons cocultured with glial cells but not in glial cultures alone. Similar results were observed for the 5-HT-stimulated release of inositol phosphates. These results suggest a neural but not glial origin of both responses....

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Felder, C C, Kanterman, R Y, Ma, A L, Axelrod, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1990
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53651/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2315313/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.6.2187
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