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Allosteric determinants in guanine nucleotide-binding proteins
Members of the G protein superfamily contain nucleotide-dependent switches that dictate the specificity of their interactions with binding partners. Using a sequence-based method termed statistical coupling analysis (SCA), we have attempted to identify the allosteric core of these proteins, the netw...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283611/ https://ncbi.nlm.nih.gov/pubmed/14623969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835919100 |
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