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Allosteric determinants in guanine nucleotide-binding proteins

Members of the G protein superfamily contain nucleotide-dependent switches that dictate the specificity of their interactions with binding partners. Using a sequence-based method termed statistical coupling analysis (SCA), we have attempted to identify the allosteric core of these proteins, the netw...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hatley, Mark E., Lockless, Steve W., Gibson, Scott K., Gilman, Alfred G., Ranganathan¶, Rama
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC283611/
https://ncbi.nlm.nih.gov/pubmed/14623969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835919100
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