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Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis
Actinobacteria produce a variety of polyketide alkaloids with unusual structures. Recently, it was shown that a type I modular polyketide synthase (PKS) is involved in the assembly of coelimycin P1, a polyketide alkaloid produced by Streptomyces coelicolor M145. However, the mechanisms for convertin...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5365063/ https://ncbi.nlm.nih.gov/pubmed/28451186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02803a |
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