Inhibiting PLK1 induces autophagy of acute myeloid leukemia cells via mammalian target of rapamycin pathway dephosphorylation

Decreased autophagy is accompanied by the development of a myeloproliferative state or acute myeloid leukemia (AML). AML cells are often sensitive to autophagy-inducing stimuli, prompting the idea that targeting autophagy can be useful in AML cytotoxic therapy. AML NB4 cells overexpressing microtubu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: Tao, Yan-Fang, Li, Zhi-Heng, Du, Wei-Wei, Xu, Li-Xiao, Ren, Jun-Li, Li, Xiao-Lu, Fang, Fang, Xie, Yi, Li, Mei, Qian, Guang-Hui, Li, Yan-Hong, Li, Yi-Ping, Li, Gang, Wu, Yi, Feng, Xing, Wang, Jian, He, Wei-Qi, Hu, Shao-Yan, Lu, Jun, Pan, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364848/
https://ncbi.nlm.nih.gov/pubmed/28184925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2017.5417
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados