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Safety and toxicology of the intravenous administration of Ang2-siRNA plasmid chitosan magnetic nanoparticles

This aim of the present study was to investigate the safety and toxicology of intravenous administration of angiopoietin-2 (Ang2)-small interfering (si)RNA plasmid-chitosan magnetic nanoparticles (CMNPs). Ang2-CMNPs were constructed and subsequently administered at different doses to mice and rats v...

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Bibliografiske detaljer
Udgivet i:Mol Med Rep
Main Authors: Shan, Xiuying, Xu, Tingting, Liu, Zhaoliang, Hu, Xuefeng, Zhang, Yan-Ding, Wang, Biao
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364838/
https://ncbi.nlm.nih.gov/pubmed/28035391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.6090
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