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A role of the SAM domain in EphA2 receptor activation

Among the 20 subfamilies of protein receptor tyrosine kinases (RTKs), Eph receptors are unique in possessing a sterile alpha motif (SAM domain) at their C-terminal ends. However, the functions of SAM domains in Eph receptors remain elusive. Here we report on a combined cell biology and quantitative...

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Publicat a:Sci Rep
Autors principals: Shi, Xiaojun, Hapiak, Vera, Zheng, Ji, Muller-Greven, Jeannine, Bowman, Deanna, Lingerak, Ryan, Buck, Matthias, Wang, Bing-Cheng, Smith, Adam W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364462/
https://ncbi.nlm.nih.gov/pubmed/28338017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45084
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