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Tolerogenic interactions between CD8(+) dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts

The combination of total lymphoid irradiation and anti-T-cell antibodies safely induces immune tolerance to combined hematopoietic cell and organ allografts in humans. Our mouse model required host natural killer T (NKT) cells to induce tolerance. Because NKT cells normally depend on signals from CD...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Hongo, David, Tang, Xiaobin, Zhang, Xiangyue, Engleman, Edgar G., Strober, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364338/
https://ncbi.nlm.nih.gov/pubmed/28096089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-07-723015
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