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Interactions between NKT cells and Tregs are required for tolerance to combined bone marrow and organ transplants
We used a model of combined bone marrow and heart transplantation, in which tolerance and stable chimerism is induced after conditioning with fractionated irradiation of the lymphoid tissues and anti–T-cell antibodies. Graft acceptance and chimerism required host CD4(+)CD25(+) Treg production of IL-...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286219/ https://ncbi.nlm.nih.gov/pubmed/22174155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-371948 |
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