Cell-cycle coupled expansion of AR activity promotes cancer progression

The androgen receptor (AR) is required for prostate cancer (PCa) survival and progression, and ablation of AR activity is the first line of therapeutic intervention for disseminated disease. While initially effective, recurrent tumors ultimately arise for which there is no durable cure. Despite the...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: McNair, Christopher, Urbanucci, Alfonso, Comstock, Clay E.S., Augello, Michael A., Goodwin, Jonathan F., Launchbury, Rosalind, Zhao, Shuang, Schiewer, Mathew J., Ertel, Adam, Karnes, Jeffrey, Davicioni, Elai, Wang, Liguo, Wang, Qianben, Mills, Ian G., Feng, Felix Y., Li, Wei, Carroll, Jason S., Knudsen, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5364060/
https://ncbi.nlm.nih.gov/pubmed/27669432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.334
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