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Complete mapping of viral escape from neutralizing antibodies

Identifying viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a high-throughput approach to quantify the selection that monoclonal antibodies exert on all single amino-acid mutations to a viral protein. Thi...

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Publicat a:PLoS Pathog
Autors principals: Doud, Michael B., Hensley, Scott E., Bloom, Jesse D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363992/
https://ncbi.nlm.nih.gov/pubmed/28288189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006271
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