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Complete mapping of viral escape from neutralizing antibodies

Identifying viral mutations that confer escape from antibodies is crucial for understanding the interplay between immunity and viral evolution. We describe a high-throughput approach to quantify the selection that monoclonal antibodies exert on all single amino-acid mutations to a viral protein. Thi...

詳細記述

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書誌詳細
出版年:PLoS Pathog
主要な著者: Doud, Michael B., Hensley, Scott E., Bloom, Jesse D.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363992/
https://ncbi.nlm.nih.gov/pubmed/28288189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006271
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