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The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt
The Notch pathway plays a vital role in determining whether cells in the intestinal epithelium adopt a secretory or an absorptive phenotype. Cell fate specification is coordinated via Notch’s interaction with the canonical Wnt pathway. Here, we propose a new mathematical model of the Notch and Wnt p...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363986/ https://ncbi.nlm.nih.gov/pubmed/28245235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005400 |
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