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HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation
UV radiations challenge genomic stability and are a recognized cancer risk factor. We previously found that the RNA-binding protein NONO regulates the intra-S phase checkpoint and its silencing impaired HeLa and melanoma cell response to UV-induced DNA damage. Here we investigated the mechanisms und...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363649/ https://ncbi.nlm.nih.gov/pubmed/27816966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13002 |
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