HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation

UV radiations challenge genomic stability and are a recognized cancer risk factor. We previously found that the RNA-binding protein NONO regulates the intra-S phase checkpoint and its silencing impaired HeLa and melanoma cell response to UV-induced DNA damage. Here we investigated the mechanisms und...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Alfano, Luigi, Costa, Caterina, Caporaso, Antonella, Antonini, Dario, Giordano, Antonio, Pentimalli, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363649/
https://ncbi.nlm.nih.gov/pubmed/27816966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13002
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