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SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro
Sirtuin 1 (SIRT1) regulates adipocyte and osteoblast differentiation. However, the underlying mechanism should be investigated. This study revealed that SIRT1 acts as a crucial repressor of adipogenesis. RNA-interference-mediated SIRT1 knockdown or genetic ablation enhances adipogenic potential, whe...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5363615/ https://ncbi.nlm.nih.gov/pubmed/27776347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12774 |
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