SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro

Sirtuin 1 (SIRT1) regulates adipocyte and osteoblast differentiation. However, the underlying mechanism should be investigated. This study revealed that SIRT1 acts as a crucial repressor of adipogenesis. RNA-interference-mediated SIRT1 knockdown or genetic ablation enhances adipogenic potential, whe...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Zhou, Yuanfei, Song, Tongxing, Peng, Jie, Zhou, Zheng, Wei, Hongkui, Zhou, Rui, Jiang, Siwen, Peng, Jian
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363615/
https://ncbi.nlm.nih.gov/pubmed/27776347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12774
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