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Biopsy proportion of tumour predicts pathological tumour response and benefit from chemotherapy in resectable oesophageal carcinoma: results from the UK MRC OE02 trial

BACKGROUND: Neoadjuvant chemotherapy followed by surgery is the standard of care for UK patients with locally advanced resectable oesophageal carcinoma (OeC). However, not all patients benefit from multimodal treatment and there is a clinical need for biomarkers which can identify chemotherapy respo...

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Pubblicato in:Oncotarget
Autori principali: Hale, Matthew D., Nankivell, Matthew, Hutchins, Gordon G., Stenning, Sally P., Langley, Ruth E., Mueller, Wolfram, West, Nicholas P., Wright, Alexander I., Treanor, Darren, Hewitt, Lindsay C., Allum, William H., Cunningham, David, Hayden, Jeremy D., Grabsch, Heike I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363605/
https://ncbi.nlm.nih.gov/pubmed/27769054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12723
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