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Overexpression of OCT4 is associated with gefitinib resistance in non-small cell lung cancer

Epidermal growth factor receptor (EGFR)-targeted tyrosine kinase inhibitors (TKIs) have emerged as first-line drugs for non-small cell lung cancers (NSCLCs). However, the resistance to TKIs represents the key limitation for their therapeutic efficacy. We found that the difference of OCT4 expression...

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Publicat a:Oncotarget
Autors principals: Li, Bin, Yao, Zhouhong, Wan, Yunyan, Lin, Dianjie
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363589/
https://ncbi.nlm.nih.gov/pubmed/27816965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12999
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