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Mitochondrial aldehyde dehydrogenase obliterates insulin resistance-induced cardiac dysfunction through deacetylation of PGC-1α

Insulin resistance contributes to the high prevalence of type 2 diabetes mellitus, leading to cardiac anomalies. Emerging evidence depicts a pivotal role for mitochondrial injury in oxidative metabolism and insulin resistance. Mitochondrial aldehyde dehydrogenase (ALDH2) is one of metabolic enzymes...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Hu, Nan, Ren, Jun, Zhang, Yingmei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363518/
https://ncbi.nlm.nih.gov/pubmed/27634872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11977
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