Mitochondrial Aldehyde Dehydrogenase Obliterates Endoplasmic Reticulum Stress-Induced Cardiac Contractile Dysfunction via Correction of Autophagy

ER stress triggers myocardial contractile dysfunction while effective therapeutic regimen is still lacking. Mitochondrial aldehyde dehydrogenase (ALDH2), an essential mitochondrial enzyme governing mitochondrial and cardiac function, displays distinct beneficial effect on the heart. This study was d...

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Detalhes bibliográficos
Main Authors: Zhang, Bingfang, Zhang, Yingmei, La Cour, Karissa H., Richmond, Kacy L., Wang, Xiaoming, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578096/
https://ncbi.nlm.nih.gov/pubmed/23354068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.01.013
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