Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids

Neovascular age-related macular degeneration (nvAMD) is characterized by choroidal blood vessels growing into the subretinal space, leading to retinal pigment epithelial (RPE) cell degeneration and vision loss. Vessel growth results from an imbalance of pro-angiogenic (e.g., vascular endothelial gro...

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Dettagli Bibliografici
Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Thumann, Gabriele, Harmening, Nina, Prat-Souteyrand, Cécile, Marie, Corinne, Pastor, Marie, Sebe, Attila, Miskey, Csaba, Hurst, Laurence D., Diarra, Sabine, Kropp, Martina, Walter, Peter, Scherman, Daniel, Ivics, Zoltán, Izsvák, Zsuzsanna, Johnen, Sandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363513/
https://ncbi.nlm.nih.gov/pubmed/28325297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.02.002
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