Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids

Neovascular age-related macular degeneration (nvAMD) is characterized by choroidal blood vessels growing into the subretinal space, leading to retinal pigment epithelial (RPE) cell degeneration and vision loss. Vessel growth results from an imbalance of pro-angiogenic (e.g., vascular endothelial gro...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Thumann, Gabriele, Harmening, Nina, Prat-Souteyrand, Cécile, Marie, Corinne, Pastor, Marie, Sebe, Attila, Miskey, Csaba, Hurst, Laurence D., Diarra, Sabine, Kropp, Martina, Walter, Peter, Scherman, Daniel, Ivics, Zoltán, Izsvák, Zsuzsanna, Johnen, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363513/
https://ncbi.nlm.nih.gov/pubmed/28325297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.02.002
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