Understanding the Genomic Structure of Copy‐Number Variation of the Low‐Affinity Fcγ Receptor Region Allows Confirmation of the Association of FCGR3B Deletion with Rheumatoid Arthritis

Fcγ receptors are a family of cell–surface receptors that are expressed by a host of different innate and adaptive immune cells, and mediate inflammatory responses by binding the Fc portion of immunoglobulin G. In humans, five low‐affinity receptors are encoded by the genes FCGR2A, FCGR2B, FCGR2C, F...

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Bibliografiset tiedot
Julkaisussa:Hum Mutat
Päätekijät: Rahbari, Raheleh, Zuccherato, Luciana W, Tischler, German, Chihota, Belinda, Ozturk, Hasret, Saleem, Sara, Tarazona‐Santos, Eduardo, Machado, Lee R, Hollox, Edward J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363352/
https://ncbi.nlm.nih.gov/pubmed/27995740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23159
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