Understanding the Genomic Structure of Copy‐Number Variation of the Low‐Affinity Fcγ Receptor Region Allows Confirmation of the Association of FCGR3B Deletion with Rheumatoid Arthritis

Fcγ receptors are a family of cell–surface receptors that are expressed by a host of different innate and adaptive immune cells, and mediate inflammatory responses by binding the Fc portion of immunoglobulin G. In humans, five low‐affinity receptors are encoded by the genes FCGR2A, FCGR2B, FCGR2C, F...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hum Mutat
Auteurs principaux: Rahbari, Raheleh, Zuccherato, Luciana W, Tischler, German, Chihota, Belinda, Ozturk, Hasret, Saleem, Sara, Tarazona‐Santos, Eduardo, Machado, Lee R, Hollox, Edward J
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363352/
https://ncbi.nlm.nih.gov/pubmed/27995740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23159
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