Understanding the Genomic Structure of Copy‐Number Variation of the Low‐Affinity Fcγ Receptor Region Allows Confirmation of the Association of FCGR3B Deletion with Rheumatoid Arthritis

Fcγ receptors are a family of cell–surface receptors that are expressed by a host of different innate and adaptive immune cells, and mediate inflammatory responses by binding the Fc portion of immunoglobulin G. In humans, five low‐affinity receptors are encoded by the genes FCGR2A, FCGR2B, FCGR2C, F...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mutat
Prif Awduron: Rahbari, Raheleh, Zuccherato, Luciana W, Tischler, German, Chihota, Belinda, Ozturk, Hasret, Saleem, Sara, Tarazona‐Santos, Eduardo, Machado, Lee R, Hollox, Edward J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363352/
https://ncbi.nlm.nih.gov/pubmed/27995740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23159
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