INSPIIRED: A Pipeline for Quantitative Analysis of Sites of New DNA Integration in Cellular Genomes

Integration of new DNA into cellular genomes mediates replication of retroviruses and transposons; integration reactions have also been adapted for use in human gene therapy. Tracking the distributions of integration sites is important to characterize populations of transduced cells and to monitor p...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Sherman, Eric, Nobles, Christopher, Berry, Charles C., Six, Emmanuelle, Wu, Yinghua, Dryga, Anatoly, Malani, Nirav, Male, Frances, Reddy, Shantan, Bailey, Aubrey, Bittinger, Kyle, Everett, John K., Caccavelli, Laure, Drake, Mary J., Bates, Paul, Hacein-Bey-Abina, Salima, Cavazzana, Marina, Bushman, Frederic D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363316/
https://ncbi.nlm.nih.gov/pubmed/28344990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2016.11.002
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