Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein

Lentiviral vectors (LVs) are a highly valuable tool for gene transfer currently exploited in basic, applied, and clinical studies. Their optimization is therefore very important for the field of vectorology and gene therapy. A key molecule for LV function is the envelope because it guides cell entry...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Methods Clin Dev
Hauptverfasser: Zucchelli, Eleonora, Pema, Monika, Stornaiuolo, Anna, Piovan, Claudia, Scavullo, Cinzia, Giuliani, Erica, Bossi, Sergio, Corna, Stefano, Asperti, Claudia, Bordignon, Claudio, Rizzardi, Gian-Paolo, Bovolenta, Chiara
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363313/
https://ncbi.nlm.nih.gov/pubmed/28344996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2017.01.002
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