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Therapeutic miR-21 Silencing Ameliorates Diabetic Kidney Disease in Mice

Diabetic nephropathy is the main cause of end-stage renal disease. MicroRNAs are powerful regulators of the genome, and global expression profiling revealed miR-21 to be among the most highly regulated microRNAs in kidneys of mice with diabetic nephropathy. In kidney biopsies of diabetic patients, m...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Kölling, Malte, Kaucsar, Tamas, Schauerte, Celina, Hübner, Anika, Dettling, Angela, Park, Joon-Keun, Busch, Martin, Wulff, Xaver, Meier, Matthias, Scherf, Kristian, Bukosza, Nóra, Szénási, Gábor, Godó, Mária, Sharma, Amit, Heuser, Michael, Hamar, Peter, Bang, Claudia, Haller, Hermann, Thum, Thomas, Lorenzen, Johan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363308/
https://ncbi.nlm.nih.gov/pubmed/28129112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.08.001
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