Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE),...

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Bibliografske podrobnosti
izdano v:PeerJ
Main Authors: Chang, Ping, Mo, Bing, Cauvi, David M., Yu, Ying, Guo, Zhenhui, Zhou, Jian, Huang, Qiong, Yan, Qitao, Chen, Guiming, Liu, Zhanguo
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2017
Teme:
Cell Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363264/
https://ncbi.nlm.nih.gov/pubmed/28344907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3108
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