Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE),...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Chang, Ping, Mo, Bing, Cauvi, David M., Yu, Ying, Guo, Zhenhui, Zhou, Jian, Huang, Qiong, Yan, Qitao, Chen, Guiming, Liu, Zhanguo
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2017
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363264/
https://ncbi.nlm.nih.gov/pubmed/28344907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3108
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