Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE),...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Chang, Ping, Mo, Bing, Cauvi, David M., Yu, Ying, Guo, Zhenhui, Zhou, Jian, Huang, Qiong, Yan, Qitao, Chen, Guiming, Liu, Zhanguo
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363264/
https://ncbi.nlm.nih.gov/pubmed/28344907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3108
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