Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE),...

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Detalles Bibliográficos
Publicado en:PeerJ
Autores principales: Chang, Ping, Mo, Bing, Cauvi, David M., Yu, Ying, Guo, Zhenhui, Zhou, Jian, Huang, Qiong, Yan, Qitao, Chen, Guiming, Liu, Zhanguo
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2017
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363264/
https://ncbi.nlm.nih.gov/pubmed/28344907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3108
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