Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE),...

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Enregistré dans:
Détails bibliographiques
Publié dans:PeerJ
Auteurs principaux: Chang, Ping, Mo, Bing, Cauvi, David M., Yu, Ying, Guo, Zhenhui, Zhou, Jian, Huang, Qiong, Yan, Qitao, Chen, Guiming, Liu, Zhanguo
Format: Artigo
Langue:Inglês
Publié: PeerJ Inc. 2017
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363264/
https://ncbi.nlm.nih.gov/pubmed/28344907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3108
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