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Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42

β‐amyloid 1‐42 (Aβ1‐42) is a self‐assembling peptide that goes through many conformational and morphological changes before forming the fibrils that are deposited in extracellular plaques characteristic of Alzheimer's disease. The link between Aβ1‐42 structure and toxicity is of major interest,...

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Bibliografiske detaljer
Udgivet i:FEBS Lett
Main Authors: Vadukul, Devkee M., Gbajumo, Oyinkansola, Marshall, Karen E., Serpell, Louise C.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363225/
https://ncbi.nlm.nih.gov/pubmed/28185264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12590
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