Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis

The pericardial fluid (PF) is contained in the pericardial sac surrounding the heart. MicroRNA (miRNA) exchange via exosomes (endogenous nanoparticles) contributes to cell-to-cell communication. We investigated the hypotheses that the PF is enriched with miRNAs secreted by the heart and that it medi...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Beltrami, Cristina, Besnier, Marie, Shantikumar, Saran, Shearn, Andrew I.U., Rajakaruna, Cha, Laftah, Abas, Sessa, Fausto, Spinetti, Gaia, Petretto, Enrico, Angelini, Gianni D., Emanueli, Costanza
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363195/
https://ncbi.nlm.nih.gov/pubmed/28159509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.12.022
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