Coronary Artery-Bypass-Graft Surgery Increases the Plasma Concentration of Exosomes Carrying a Cargo of Cardiac MicroRNAs: An Example of Exosome Trafficking Out of the Human Heart with Potential for Cardiac Biomarker Discovery

INTRODUCTION: Exosome nanoparticles carry a composite cargo, including microRNAs (miRs). Cultured cardiovascular cells release miR-containing exosomes. The exosomal trafficking of miRNAs from the heart is largely unexplored. Working on clinical samples from coronary-artery by-pass graft (CABG) surge...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Emanueli, Costanza, Shearn, Andrew I. U., Laftah, Abas, Fiorentino, Francesca, Reeves, Barnaby C., Beltrami, Cristina, Mumford, Andrew, Clayton, Aled, Gurney, Mark, Shantikumar, Saran, Angelini, Gianni D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851293/
https://ncbi.nlm.nih.gov/pubmed/27128471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154274
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