Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice

In vitro and ex vivo experiments indicate that elastase-2 (ELA-2), a chymotrypsin-serine protease elastase family member 2A, is an alternative pathway for angiotensin II (Ang II) generation. However, the role played by ELA-2 in vivo is unclear. We examined ELA-2 knockout (ELA-2KO) mice compared to w...

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Detalles Bibliográficos
Publicado en:Front Physiol
Main Authors: Becari, Christiane, Durand, Marina T., Guimaraes, Alessander O., Lataro, Renata M., Prado, Cibele M., de Oliveira, Mauro, Candido, Sarai C. O., Pais, Paloma, Ribeiro, Mauricio S., Bader, Michael, Pesquero, Joao B., Salgado, Maria C. O., Salgado, Helio C.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363176/
https://ncbi.nlm.nih.gov/pubmed/28386233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00170
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