Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice

In vitro and ex vivo experiments indicate that elastase-2 (ELA-2), a chymotrypsin-serine protease elastase family member 2A, is an alternative pathway for angiotensin II (Ang II) generation. However, the role played by ELA-2 in vivo is unclear. We examined ELA-2 knockout (ELA-2KO) mice compared to w...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Physiol
Egile Nagusiak: Becari, Christiane, Durand, Marina T., Guimaraes, Alessander O., Lataro, Renata M., Prado, Cibele M., de Oliveira, Mauro, Candido, Sarai C. O., Pais, Paloma, Ribeiro, Mauricio S., Bader, Michael, Pesquero, Joao B., Salgado, Maria C. O., Salgado, Helio C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2017
Gaiak:
Physiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363176/
https://ncbi.nlm.nih.gov/pubmed/28386233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00170
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