Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging

BACKGROUND: Accurate measurement of tumor burden in breast cancer disease is essential to improve the clinical management of patients. In this study, we evaluate whether the fluctuations in the fraction of PIK3CA mutant allele correlates with tumor response according to RECIST criteria and tumor mar...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: García-Saenz, José Angel, Ayllón, Patricia, Laig, Marion, Acosta-Eyzaguirre, Daniel, García-Esquinas, Marta, Montes, Myriam, Sanz, Julián, Barquín, Miguel, Moreno, Fernando, Garcia-Barberan, Vanesa, Díaz-Rubio, Eduardo, Caldes, Trinidad, Romero, Atocha
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362993/
https://ncbi.nlm.nih.gov/pubmed/28330468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3185-9
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