Tumor burden monitoring using cell-free tumor DNA could be limited by tumor heterogeneity in advanced breast cancer and should be evaluated together with radiographic imaging

BACKGROUND: Accurate measurement of tumor burden in breast cancer disease is essential to improve the clinical management of patients. In this study, we evaluate whether the fluctuations in the fraction of PIK3CA mutant allele correlates with tumor response according to RECIST criteria and tumor mar...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: García-Saenz, José Angel, Ayllón, Patricia, Laig, Marion, Acosta-Eyzaguirre, Daniel, García-Esquinas, Marta, Montes, Myriam, Sanz, Julián, Barquín, Miguel, Moreno, Fernando, Garcia-Barberan, Vanesa, Díaz-Rubio, Eduardo, Caldes, Trinidad, Romero, Atocha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362993/
https://ncbi.nlm.nih.gov/pubmed/28330468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3185-9
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