Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell

MicroRNAs have emerged as important players of gene regulation with significant impact in diverse disease processes. In type-2 diabetes, in which impaired insulin secretion is a major factor in disease progression, dysregulated microRNA expression in the insulin-secreting pancreatic beta cell has be...

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Vydáno v:Sci Rep
Hlavní autoři: Ofori, Jones K., Salunkhe, Vishal A., Bagge, Annika, Vishnu, Neelanjan, Nagao, Mototsugu, Mulder, Hindrik, Wollheim, Claes B., Eliasson, Lena, Esguerra, Jonathan L. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362944/
https://ncbi.nlm.nih.gov/pubmed/28332581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44986
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