Structural insights into the nucleotide base specificity of P2X receptors

P2X receptors are trimeric ATP-gated cation channels involved in diverse physiological processes, ranging from muscle contraction to nociception. Despite the recent structure determination of the ATP-bound P2X receptors, the molecular mechanism of the nucleotide base specificity has remained elusive...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kasuya, Go, Fujiwara, Yuichiro, Tsukamoto, Hisao, Morinaga, Satoshi, Ryu, Satoshi, Touhara, Kazushige, Ishitani, Ryuichiro, Furutani, Yuji, Hattori, Motoyuki, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362899/
https://ncbi.nlm.nih.gov/pubmed/28332633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45208
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