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Discovery of multi-target receptor tyrosine kinase inhibitors as novel anti-angiogenesis agents

Recently, we have identified a biphenyl-aryl urea incorporated with salicylaldoxime (BPS-7) as an anti-angiogenesis agent. Herein, we disclosed a series of novel anti-angiogenesis agents with BPS-7 as lead compound through combining diarylureas with N-pyridin-2-ylcyclopropane carboxamide. Several ti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Jinfeng, Zhang, Lin, Pan, Xiaoyan, Dai, Bingling, Sun, Ying, Li, Chuansheng, Zhang, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362808/
https://ncbi.nlm.nih.gov/pubmed/28332573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45145
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