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Proteoform Profile Mapping of the Human Serum Complement Component C9 Revealing Unexpected New Features of N-, O-, and C-Glycosylation

[Image: see text] The human complement C9 protein (∼65 kDa) is a member of the complement pathway. It plays an essential role in the membrane attack complex (MAC), which forms a lethal pore on the cellular surface of pathogenic bacteria. Here, we charted in detail the structural microheterogeneity o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Anal Chem
Prif Awduron: Franc, Vojtech, Yang, Yang, Heck, Albert J. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2017
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362742/
https://ncbi.nlm.nih.gov/pubmed/28221766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b04527
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