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Contribution of LATS1 and LATS2 promoter methylation in OSCC development

The aberrant DNA methylation of the tumor suppressor genes involved in DNA Damage Response (DDR) signaling and cell cycle regulation may lead to the tumorigenesis. Our purpose here is to analyze the promoter methylation and mRNA expression levels of LATS1 and LATS2 (LATS1/2) genes in OSCC. Promoter...

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Foilsithe in:J Cell Commun Signal
Main Authors: Ladiz, Mohammad Ayoub Rigi, Najafi, Maryam, Kordi-Tamandani, Dor Mohammad
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Netherlands 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362570/
https://ncbi.nlm.nih.gov/pubmed/27761802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-016-0356-4
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